Open positions
Open research positions in SNAP group are available here.

Enhanced tissue-specific gene interaction networks

Dataset information

This is a collection of gene-gene interaction networks from various human tissues. The networks capture gene interactions that are specific to human tissues and cell lineages ranging from B lymphocyte to skeletal muscle and the whole brain. In each network, nodes represent genes and edges represent tissue-specific functional associations between genes.


Dataset statistics
Tissues 22
Nodes 25825
Edges in tissue central_nervous_system 162492721
Edges in tissue epidermis 158818170
Edges in tissue neuron 243874761
Edges in tissue heart 121110631
Edges in tissue skeletal_muscle 123841014
Edges in tissue blood_platelet 146263529
Edges in tissue chondrocyte 238930002
Edges in tissue muscle 142509370
Edges in tissue embryo 146713307
Edges in tissue smooth_muscle 179472548
Edges in tissue retina 168381960
Edges in tissue blood_plasma 156621439
Edges in tissue blood_vessel 143976571
Edges in tissue lymphocyte 141885392
Edges in tissue brain 162851895
Edges in tissue natural_killer_cell 208836746
Edges in tissue bone 158767553
Edges in tissue nervous_system 162760765
Edges in tissue cardiac_muscle 208475128
Edges in tissue t_lymphocyte 144593277
Edges in tissue b_lymphocyte 144870522
Edges in tissue blood 176787032

The networks are constructed based on raw tissue-specific gene interaction networks, which are normalized and denoised using network enhancement algorithm.

References


Files

File Size Description
GG-NE.tar.gz 19GB Gene-gene interaction networks and statistics (one network per human tissue, nodes are given by NCBI Entrez Gene IDs)