Species-specific protein-protein association networks

Dataset information

This is a collections of species-specific protein-protein association networks. Nodes represent proteins in different species (e.g., human, fruit fly, zebrafish, yeast) and edges represent direct (physical) protein-protein interactions, as well as indirect (functional) associations between proteins in a given species.

The information is extracted from STRING v10.5 and contains experimental data on protein-protein interactions, known pathways and protein complexes from curated databases, interactions based on systematic co-expression analysis, shared signals across genomes, associations obtained via automated text-mining of scientific literature, and interactions transferred between species based on gene orthology.

References

• The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible. Szklarczyk, Damian, et al. Nucleic Acids Research. 2016.
  

• MINER: Gigascale multimodal biological network. Stanford SNAP Group. GitHub Repository. 2017.
  

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